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clinicians simply describe what the patient tells us about
their symptoms and what we find on urodynamic testing.
We are pleased that Fode and Sønksen accept our
inclusion criteria of a bladder contractility index of
<
100 in
men and a detrusor pressure at maximum flow of
<
20 cm
H
2
O in women as a proposed definition of urodynamic DU.
We add that men were also required to have a bladder
outlet obstruction index (BOOI) of
<
20 and women a
maximum flow rate of
<
15 ml/s. Without a definite DU
diagnosis for our inclusion criteria, we concluded that
progress in exploring the relationship between UAB and DU
would be impossible. Fode and Sønksen also point out that
we selected symptomatic DU patients. As patients were
selected from our urodynamic database, they were
generally symptomatic, as was essential for the work
described in our paper. To accomplish our programme of
work in a reasonable period of time, we took previously
investigated patients, which is why the analysis was
retrospective.
Conflicts of interest:
Alan D. Uren, Paul Abrams, and Nikki Cotterill are
supportedby a grantfromAstellas.MoniqueKlaver, DominiqueBongaerts,
and Zalmai Hakimi are employees of Astellas Pharma Europe. Paul Abrams
has received personal fees from Astellas, Pfizer, Ferring, Ipsen, and Sun
Pharma. Nikki Cotterill has received personal fees from Procter and
Gamble. Christopher Chapple has received personal fees from Allergan,
Astellas, Medtronic, and Recordati. Christopher Harding has received
personal fees from Astellas, Pfizer, Ferring, Allergan, Medtronic, American
Medical Systems, and Pierre Fabre Pharmaceuticals.
References
[1]
Fode M, Sønksen J. Towards a greater understanding of underactive bladder. Eur Urol 2017;72:408–9.
[2]
Uren AD, Cotterill N, Harding C, et al. Qualitative exploration of the patient experience of underactive bladder. Eur Urol 2017;72:402–7.[3]
Wein A, Chapple C. Introduction and terminology. In: Chapple C, Wein A, Osman N, editors. Underactive bladder. ed. 1. Basel, Switzerland: Springer; 2017. http://dx.doi.org/10.1016/j.eururo.2017.06.039E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 4 0 8 – 4 1 0
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